GROWTH SUMMIT: ADVANCING NUTRITION SCIENCE FOR OPTIMAL CHILDHOOD GROWTH
Julian Lui, PhD
Section on Growth and Development
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Bethesda, Maryland, USA
Dr Lui reviews key regulatory mechanisms of longitudinal bone growth at the growth plate, and the impact of nutrition on growth rate and growth duration. Research findings support that children grow taller because of a functional and responsive growth plate. Nutrition plays a critical role in modulating levels and effects of hormones that impact growth rate. Research findings show that growth plate senescence is driven more by growth than time. Malnutrition, which limits growth, also has the effect of reducing the rate of growth plate senescence, thus helping enable catch up growth when adequate nutrition is restored.