Overview of Mechanism of Early Programming During Pregnancy

Publish Date: 2011
Author(s): Susan Ozanne, PhD


Extensive studies during the last 20 years have revealed that both low birth weight (especially when followed by accelerated postnatal growth) and high birth weight are associated with metabolic disease later in life. Dr Ozanne describes three categories of mechanisms by which a phenomenon that occurs in early life can have long-term effects on the function of a cell and therefore metabolism of an organism years later. The main goals now in the early programming field are to build on these findings and to translate them into ways to improve human health through development of preventative and intervention strategies.
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Author Bios

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Susan Ozanne, Phd

University of Cambridge, Department of Clinical Biochemistry, UK
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