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Urea Cycle Disorders: Navigating Nutritional Management and Nitrogen Scavengers

Program Date: 19 May 2023

Publication Date: 15 November 2023

Continuing Education Units: Nurse Contact: 1.0; Dietitian CPEU: 1.0; Physician CME: 1.0

Course Description:

In this course, Rani Singh, PhD, RD, LD will describe urea cycle disorders (UCDs) and explain the rationale for nitrogen scavengers; review the current nitrogen scavenger drugs available for the treatment of UCDs; and apply nitrogen scavenger drugs and titrating strategies to optimize nutritional management and outcomes in patients with UCDs. Originally presented live at the 19th Abbott Metabolic Conference on May 19, 2023, in San Antonio, TX.

Course Objectives:

• Describe the urea cycle disorders (UCDs) and explain the rationale for nitrogen scavengers.
• Review the current nitrogen scavenger drugs available for the treatment of UCDs.
• Apply nitrogen scavenger drugs and titrating strategies to optimize nutritional management and outcomes in patients with UCDs.

Run Time: 37

Course Instructor Bio(s)

Rani Singh, PhD, RD, LD

Professor, Emory University
Department of Human Genetics
Atlanta, GA, USA

Rani Singh, PhD, RD, LD is a Professor of Human Genetics and Pediatrics and Director of the Genetic Metabolic Nutrition Program at Emory University. She has over 25 years of research and clinical experience in the field of inborn errors of metabolism. Her clinical research interests include restricted diets, genotype-phenotype relationships, and the benefits of early metabolic identification. She's also the Primary Investigator of the HRSA grants on enhanced genetic screening, the founding member of GMDI, and the co-Primary Investigator with Fran Rohr for the Evidence-Based Nutrition Guidelines for Inborn Errors of Metabolism.

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