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Beyond Anthropometrics: Evolving Science of Biomarkers for Assessing Growth

Program Date: 18 October 2022

Publication Date: 16 March 2023

Continuing Education Units: Nurse Contact: 1.0; Dietitian CPEU: 1.0

Course Description:

In this course, Brian Johnstone, PhD, FIOR, FORS will identify the challenges for accurately measuring growth in children; discuss the potential benefits of biomarkers to evaluate real-time childhood growth; describe the development of the collagen X biomarker (CXM) assay; and discuss other potential uses for the CXM assay. Originally presented as a live webinar on October 18, 2022.

Course Objectives:

• Identify the challenges for accurately measuring growth in children.

• Discuss the potential benefits of biomarkers to evaluate real-time childhood growth.

• Describe the development of the collagen X biomarker (CXM) assay for use as a real-time marker of height velocity.

• Discuss other potential uses for the CXM assay.

CDR Level: 2
Performance Indicators: 4.1.2, 4.2.1, 10.2.1
Run Time: 27

Course Instructor Bio(s)

Brian Johnstone, PhD, FIOR, FORS

Professor, Director of Research, Orthopaedics, and Rehabilitation

Professor, Cell and Developmental Biology

Professor, Molecular and Medical Genetics

Oregon Health & Science University

Director, CXM Laboratory

Shriners Hospital, Portland

Portland, OR, USA

Brian Johnstone, PhD, FIOR, FORS is a Professor in the departments of Orthopaedics and Rehabilitation, Cell and Developmental Biology, and Molecular and Medical Genetics at Oregon Health & Science University in Portland, Oregon. There, he is also the Director of Research for Orthopaedics and Rehabilitation. He is also a staff scientist and Director of the CXM Assay Laboratory at Shriners Research Center and affiliate faculty at the Translational Medicine Institute of Colorado State University.

Prof. Johnstone completed his predoctoral research in England and postdoctoral studies in the United States. His main research area is skeletal tissue regeneration, and he has worked on articular cartilage, spine, meniscus, and temporomandibular disc. He developed and patented the system for the chondrogenic induction of stem cells. He has published 88 peer-reviewed articles (>13,000 citations, h-index of 48, i10-index of 73), with grants from numerous sources including the NIH, Arthritis Foundation, and Shriners Hospitals. In addition, he has written several reviews and book chapters and served as editor for book sections.

He is a Past-President of the Orthopaedic Research Society and has served/serves on numerous grant review panels of national and international organizations and journal editorial boards. He currently serves as the Senior Advisor to the Orthopaedic Research and Education Foundation; the Translational Medicine Institute at Colorado State University; the AO Research Institute, Switzerland; and the Technological University of Shannon, Ireland. He is also the Mercator Fellow for the German Research Foundation multicenter program in osteoarthritis. Prof. Johnstone has received numerous national and international honors and awards, including being elected into the inaugural class of Fellows of International Orthopaedic Research (FIOR), and that of the Orthopaedic Research Society Fellows (FORS). He is now chair of the FIOR College. In 2017 he was given the Marshall R. Urist Award for his contributions to tissue regeneration research.