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Human Milk Oligosaccharides: Mechanisms of Action and Emerging Science

Continuing Education Units: Nurse Contact: 1.0; Dietitian CPEU: 1.0; Physician CME: 1.0

Course Description:

In this course, David R. Hill, PhD will define the role of human milk oligosaccharides (HMOs) in infant development and health; discuss insights into the mechanism of action of HMOs; and summarize the preclinical evidence supporting the impact of HMOs on cognition, gut health, and immunity.

Course Objectives:

• Define the role of human milk oligosaccharides (HMOs) in infant development and health.

• Discuss insights into the mechanism of action of HMOs.

• Summarize the preclinical evidence supporting the impact of HMOs on cognition, gut health, and immunity.

Run Time: 36

Course Instructor Bio(s)

David R. Hill, PhD

Research Scientist

Abbott Nutrition

Columbus, OH, USA

David Hill, PhD is a Research Scientist for the Gut and Immunity Platform within the Nutrition Division at Abbott. In his present role, he designs and conducts early-stage discovery research to develop nutrition solutions to improve health and wellness in both children and adults and contributes to the translation of these discoveries into innovative new products. He earned a BS in Biological Sciences at Kent State University and completed a PhD in Molecular Medicine at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. After graduation, he completed further training in human milk biochemistry and studied the role of human milk oligosaccharides in immunity at Boston College. Prior to joining Abbott in 2019, he worked at the University of Michigan, ultimately earning an appointment as a Research Assistant Professor for his research developing stem cell-derived models of host-microbial interaction in infant gastrointestinal development. He has written more than 25 peer-reviewed scientific manuscripts and book chapters, has taught Immunology, Evolutionary Biology, and Statistics at the undergraduate and graduate level, and has mentored dozens of MS, PhD, and MD students in research.

Slav Dvoretskiy, PhD

Senior Scientist

Abbott Nutrition

Columbus, OH, USA

Dr Dvoretskiy is a Senior Pediatric Nutrition Scientist at Abbott Nutrition, where he provides scientific support for multiple pediatric nutrition products. His focus areas at Abbott Nutrition include human milk oligosaccharides (HMOs) and pediatric nutrition. He holds a Bachelor’s, Master’s, and PhD degrees in Kinesiology through the University of Illinois at Urbana-Champaign. He then went on to complete his post-doctoral training at the Beckman Institute for Advanced Science and Technology at the University of Illinois. While at UIUC, his research was very broad ranging from molecular muscle physiology to stem cell/exosome biology. He received multiple prestigious awards including NIH T32 Tissue Microenvironment Fellowship and ACSM NASA Space Physiology grant. Dr Dvoretskiy published over 10 articles in peer-reviewed journals, in addition to abstracts and presentations in the field.

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